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Article

HER2/ERBB2 copy number analysis by targeted next-generation sequencing in breast cancer

16 Dec 2023

Abstract excerpt

OBJECTIVES: A combination of immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) is the current standard of care for HER2 evaluation in breast cancer. Here, we investigate the potential clinical utility of next-generation sequencing (NGS)-derived HER2/ERBB2 copy number (CN) data for predicting HER2 status as defined by American Society of Clinical Oncology (ASCO)/College of American...

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PMID: 38104247
DOI: 10.1093/ajcp/aqad167

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