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Article

Precise ERBB2 copy number assessment in breast cancer by means of molecular inversion probe array analysis.

Oncotarget - 13 Dec 2016

Christgen Matthias, van Luttikhuizen Jana L, Raap Mieke, Braubach Peter, Schmidt Lars, Jonigk Danny, Feuerhake Friedrich, Lehmann Ulrich, Schlegelberger Brigitte, Kreipe Hans H, Steinemann Doris

Abstract excerpt

HER2/ERBB2 amplification/overexpression determines the eligibility of breast cancer patients to HER2-targeted therapy. This study evaluates the agreement between ERBB2 copy number assessment by fluorescence in situ hybridization, a standard method recommended by the American Society of Clinical O...

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Topics

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Share to Gene Amplification
Share to Gene Dosage
Share to In Situ Hybridization, Fluorescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Molecular Probe Techniques

Share to Oligonucleotide Array Sequence Analysis

Share to Predictive Value of Tests

Share to Receptor, ErbB-2

Share to Reproducibility of Results

Source

Open in PubMed Open full text

Identifiers

PMID: 27716627
DOI: 10.18632/oncotarget.12421
PMCID: PMC5347728

Genes

ERBB2
MIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-27716627-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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