Article
Association between clonal hematopoiesis-related gene mutations and unfavorable functional outcome in patients with large-artery atherosclerotic stroke.
European journal of medical research - 16 Dec 2023
Qiu Xin, Weng Jiaxu, Jiang Yingyu, Cui Lingyun, Gu Hongqiu, Jiang Yong, Dai Yalun, Li Hao, Wang Yongjun, Li Zixiao
Abstract excerpt
BACKGROUND: Clonal hematopoiesis of indeterminate potential (CHIP) is a phenomenon that characterizes individuals with somatic mutations that are related to hematologic malignancy but without hematologic abnormalities. Presence of CHIP is associated with the atherosclerotic cardiovascular disease through the activation of the interleukin 6 (IL-6) pathway; however, its role on unfavorable functional outcomes in...
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