Article
Associations of clonal hematopoiesis with recurrent vascular events and death in patients with incident ischemic stroke.
Blood - 16 Feb 2023
Arends Christopher M, Liman Thomas G, Strzelecka Paulina M, Kufner Anna, Löwe Pelle, Huo Shufan, Stein Catarina M, Piper Sophie K, Tilgner Marlon, Sperber Pia S, Dimitriou Savvina, Heuschmann Peter U, Hablesreiter Raphael, Harms Christoph, Bullinger Lars, Weber Joachim E, Endres Matthias, Damm Frederik
Abstract excerpt
Clonal hematopoiesis (CH) is common among older people and is associated with an increased risk of atherosclerosis, inflammation, and shorter overall survival. Age and inflammation are major risk factors for ischemic stroke, yet the association of CH with risk of secondary vascular events and death is unknown. We investigated CH in peripheral blood DNA from 581 patients with first-ever ischemic stroke from the...
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