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Article

Effect of clonal hematopoiesis on plaque morphology and prognosis in patients with acute myocardial infarction.

Genome medicine - 25 Aug 2025

Li Jiannan, Chen Runzhen, Zhou Jinying, Li Nan, Zhou Peng, Liu Chen, Song Li, Zhao Xiaoxiao, Chen Yi, Yan Shaodi, Yan Hongbing, Tan Yu, Zhao Hanjun

Abstract excerpt

BACKGROUND: Clonal hematopoiesis of indeterminate potential (CHIP) is related to cardiovascular disorders and poor prognosis. However, the relationship between CHIP and clinical outcome as well as pathological phenotype of patients with acute myocardial infarction was unknown. Herein, we aimed to investigate the associations between CHIP mutation stratified by variant allele frequency (VAF) from 0.5% to 2% and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40855342
DOI: 10.1186/s13073-025-01531-8
PMCID: PMC12376346

Genes

ASXL1
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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