Article
Somatic mutation contributing to clonal haematopoiesis is a risk factor of recurrent stroke in first-ever acute ischaemic stroke: a prospective cohort study.
Stroke and vascular neurology - 1 Apr 2023
Qiu Xin, Dai Yalun, Cheng Si, Gu Hong-Qiu, Jiang Yong, Meng Xia, Wang Yilong, Zhao Xingquan, Jiang Yingyu, Xu Zhe, Huang Xinying, Wang Meng, Lyu Tian Jie, Wang Yubo, Weng Jiaxu, Cui Lingyun, Shangguan Yi, Li Hao, Wang Yongjun, Li Zixiao
Abstract excerpt
BACKGROUND: Somatic mutation contributes to clonal haematopoiesis of indeterminate potential (CHIP) is related to age and associated with a higher risk of stroke and atherosclerotic cardiovascular disease. Here, we investigated the prognostic significance of CHIP in a large first-ever acute ischaemic stroke (AIS) cohort and explored the underlying mechanisms. METHODS: We studied a prospective cohort of 6016...
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