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Article

Single-Nucleus Analysis Reveals Tumor Heterogeneity of Aldosterone-Producing Adenoma.

Hypertension (Dallas, Tex. : 1979) - 1 Feb 2024

Murakami Masanori, Hara Kazunari, Ikeda Kenji, Horino Masato, Okazaki Rei, Niitsu Yoshihiro, Takeuchi Akira, Aoki Jun, Shiba Kumiko, Tsujimoto Kazutaka, Komiya Chikara, Nakamura Yuki, Kurata Morito, Akashi Takumi, Fujii Yasuhisa, Yamada Tetsuya

Abstract excerpt

BACKGROUND: Recent advances in omics techniques have allowed detailed genetic characterization of aldosterone-producing adenoma (APA). The pathogenesis of APA is characterized by tumorigenesis-associated aldosterone synthesis. The pathophysiological intricacies of APAs have not yet been elucidated at the level of individual cells. Therefore, a single-cell level analysis is speculated to be valuable in studying...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to G Protein-Coupled Inwardly-Rectifying Potassium Channels

Share to KCNJ5 gene

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Source

Identifiers

PMID: 38095094
DOI: 10.1161/HYPERTENSIONAHA.123.21446

Genes

KCNJ5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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