Article

Extensive patient-to-patient single nuclei transcriptome heterogeneity in pheochromocytomas and paragangliomas

2022-05-05

Abstract excerpt

<h4>ABSTRACT</h4> Pheochromocytomas (PC) and paragangliomas (PG) are rare neuroendocrine tumors of varied genetic makeup, associated with high cardiovascular morbidity and a variable risk of malignancy. The source of the transcriptional heterogeneity of the disease and the underlying biological processes determining the outcome in PCPG remains largely unclear. We focused on PCPG tumors with germline SDHB and RET...

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Literature Corpus work: 5f710a3c-f3b8-59ff-aef4-fed7a82be4e3
DOI: 10.1101/2022.05.05.489848

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