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Targeting epigenetic and posttranslational modifications regulating ferroptosis for the treatment of diseases

10 Dec 2023

Abstract excerpt

Ferroptosis, a unique modality of cell death with mechanistic and morphological differences from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a new opportunity for modulating anticancer drug resistance. Aberrant epigenetic modifications and posttranslational modifications (PTMs) promote anticancer drug resistance, cancer progression, and metastasis. Accumulating studies...

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Share to Epigenetics and DNA Methylation
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PMID: 38072908
DOI: 10.1038/s41392-023-01720-0

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