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Systematic Analysis of the Aberrances and Functional Implications of Ferroptosis in Cancer

20 Jun 2020

Abstract excerpt

Ferroptosis is a type of cell death related to cancer; however, the characteristics of ferroptosis in cancers are still uncertain. Based on the data in The Cancer Genome Atlas, we found that most ferroptosis regulator genes (FRGs) were differentially expressed in tumors, somatic copy number alterations (SCNA) and DNA methylation contributed to their aberrant expression. We established the ferroptosis potential...

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PMID: 32629423
DOI: 10.1016/j.isci.2020.101302

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