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Ferroptosis: Biochemistry and Biology in Cancers

1 Apr 2021

Abstract excerpt

The challenge of eradicating cancer is that cancer cells possess diverse mechanisms to protect themselves from clinical strategies. Recently, ferroptosis has been shown to exhibit appreciable anti-tumor activity that could be harnessed for cancer therapy in the future. Ferroptosis is an iron-dependent form of regulated cell death that is characterized by the oxidization of polyunsaturated fatty acids (PUFAs) and...

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PMID: 33868986
DOI: 10.3389/fonc.2021.579286

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