Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The DNA glycosylase NEIL2 is protective during SARS-CoV-2 infection

9 Dec 2023

Abstract excerpt

SARS-CoV-2 infection-induced aggravation of host innate immune response not only causes tissue damage and multiorgan failure in COVID-19 patients but also induces host genome damage and activates DNA damage response pathways. To test whether the compromised DNA repair capacity of individuals modulates the severity of COVID-19 infection, we analyze DNA repair gene expression in publicly available patient datasets...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immunotherapy and Immune Responses
Share to RNA Interference and Gene Delivery
Share to SARS-CoV-2 and COVID-19 Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38071370
DOI: 10.1038/s41467-023-43938-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The DNA glycosylase NEIL2 is protective during SARS-CoV-2 infectionPMID 38071370Read ↗

The DNA glycosylase NEIL2 plays a vital role in combating SARS-CoV-2 infectionSemantic proximity Read ↗

Functional roles and cancer variants of the bifunctional glycosylase NEIL2Semantic proximity Read ↗

DNA damage response at telomeres boosts the transcription of SARS‐CoV‐2 receptor ACE2 during agingSemantic proximity Read ↗

Suppression of the DNA repair enzyme NEIL2 promotes persistent inflammation and genomic damage in subjects with stable COPD and during severe exacerbationsSemantic proximity Read ↗

DNA damage contributes to age‐associated differences in SARS‐CoV ‐2 infectionSemantic proximity Read ↗

Identification and validation of Nei-like DNA glycosylase 2 as a novel prognostic biomarker in cervical cancerSemantic proximity Read ↗

Unique structural features of mammalian NEIL2 DNA glycosylase prime its activity for diverse DNA substrates and environmentsSemantic proximity Read ↗

An Immune Epigenetic Insight to COVID-19 InfectionSemantic proximity Read ↗

Increased risk of lung cancer associated with a functionally impaired polymorphic variant of the human DNA glycosylase NEIL2.Semantic proximity Read ↗

The SARS-CoV-2 host cell receptor ACE2 correlates positively with immunotherapy response and is a potential protective factor for cancer progressionSemantic proximity Read ↗

DNA glycosylase NEIL2 prevents <i>Fusobacterium</i> -mediated inflammation and DNA damage in colonic epithelial cellsSemantic proximity Read ↗

SARS-CoV-2 nucleocapsid uniquely disrupts chromatin over pathophysiologically relevant gene promotersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.