Article

DNA glycosylase NEIL2 prevents <i>Fusobacterium</i> -mediated inflammation and DNA damage in colonic epithelial cells

2020-06-12

Abstract excerpt

Colorectal cancer (CRC) is the third most prevalent and deadly cancer. Approximately, 15-20 % of CRCs display microsatellite instability (MSI); however, the majority ( 80–85 %) of cases are sporadic and known as microsatellite stable (MSS). Several recent studies indicated that infection and uncontrolled inflammation initiate DNA damage and lead to cancer progression. One of the major microbes, Fusobacterium nuc...

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Literature Corpus work: 6d136a2e-45bf-5c68-a6fb-2416ff70b7ab
DOI: 10.1101/2020.06.11.147454

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