Article

Frequent whole blood donations select for DNMT3A variants mediating enhanced response to erythropoietin

2022-07-29

Abstract excerpt

<h4>Background</h4> Blood donation saves lives. Provided they are in good health, male volunteers can donate as often as six times per year from the age of 18 into their late sixties. The burden of blood donation is very unevenly distributed, with a small minority of altruistic individuals providing this critical resource. While the consequences of persistent iron depletion in blood donors have been studied in the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9c1ee1fa-76f6-58f9-b89e-213c2fb94631
DOI: 10.1101/2022.07.24.22277825

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Frequent whole blood donations select for DNMT3A variants mediating enhanced response to erythropoietinDOI 10.1101/2022.07.24.22277825Read

Clonal hematopoiesis landscape in frequent blood donors.Semantic proximity Read

Clonal hematopoiesis in frequent whole blood donors.Semantic proximity Read

Regular Blood Donation: Does It Have a Clinical Impact on Donor Health?Semantic proximity Read

Characterization of clonal dynamics using duplex sequencing in donor-recipient pairs decades after hematopoietic cell transplantation.Semantic proximity Read

A population-scale Red Blood Cell proteome atlas of 13,000 donors uncovers genetically encoded aging clocks predicting hemolysis, transfusion efficacy, and donor activity a decade laterSemantic proximity Read

Genetic and behavioral modification of hemoglobin and iron status among first-time and high-intensity blood donors.Semantic proximity Read

Poor mobilization of autologous CD34+ peripheral blood stem cells in haematology patients undergoing autologous stem cell transplantation is associated with the presence of variants in genes implicated in clonal haematopoiesis of indeterminant potential.Semantic proximity Read

Donor clonal hematopoiesis and recipient outcomes after transplantationSemantic proximity Read

Stem Cell Technology Provides Novel Tools to Understand the Impact of Human Variation on MalariaSemantic proximity Read

STEM CELL TECHNOLOGY PROVIDES NOVEL TOOLS TO UNDERSTAND HUMAN VARIATION IN <i>Plasmodium falciparum</i> MALARIASemantic proximity Read

International Forum on Blood Donation in Individuals with Current, Past or Germline Predisposition to Malignancy: Responses.Semantic proximity Read

A decadal profile of RhD-negative blood donors in Chongqing, China: demographics, phenotypic diversity, and donation behavior.Semantic proximity Read