Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sperm chromatin accessibility’s involvement in the intergenerational effects of stress hormone receptor activation

8 Dec 2023

Abstract excerpt

Dexamethasone is a stress hormone receptor agonist used widely in clinics. We and others previously showed that paternal administration of dexamethasone in mice affects the phenotype of their offspring. The substrate of intergenerational transmission of environmentally induced effects often involves changes in sperm RNA, yet other epigenetic modifications in the germline can be affected and are also plausible...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Reproductive System and Pregnancy
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38065942
DOI: 10.1038/s41398-023-02684-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sperm chromatin accessibility’s involvement in the intergenerational effects of stress hormone receptor activationPMID 38065942Read ↗

Adult Glucocorticoid Exposure Leads to Transcriptional and DNA Methylation Changes in Nuclear Steroid Receptors in the Hippocampus and Kidney of Mouse Male Offspring1Semantic proximity Read ↗

Epididymal glucocorticoid receptors promote intergenerational transmission of paternal stressSemantic proximity Read ↗

Differential susceptibility of male and female germ cells to glucocorticoid-mediated signalingSemantic proximity Read ↗

Transgenerational paternal transmission of acquired traits: stress-induced modification of the sperm regulatory transcriptome and offspring phenotypesSemantic proximity Read ↗

A novel mode of communication between blood and the germline for the inheritance of paternal experiencesSemantic proximity Read ↗

Alterations in sperm long RNA contribute to the epigenetic inheritance of the effects of postnatal traumaSemantic proximity Read ↗

Alterations in sperm long RNA contribute to the epigenetic inheritance of the effects of postnatal traumaSemantic proximity Read ↗

Epigenetic Alterations Associated With Early Prenatal Dexamethasone TreatmentSemantic proximity Read ↗

Small Noncoding RNAs Contribute to Sperm Oxidative Stress-Induced Programming of Behavioral and Metabolic Phenotypes in Offspring.Semantic proximity Read ↗

Increased paternal corticosterone exposure preconception shifts offspring social behaviours and expression of urinary pheromonesSemantic proximity Read ↗

Elevated paternal glucocorticoid exposure alters the small noncoding RNA profile in sperm and modifies anxiety and depressive phenotypes in the offspring.Semantic proximity Read ↗

Molecular and organismal changes in offspring of male mice treated with chemical stressors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.