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Epididymal glucocorticoid receptors promote intergenerational transmission of paternal stress

2018-05-15

Abstract excerpt

Paternal preconception exposures and insults, including stress, dietary challenge and drugs of abuse, can shape offspring health and disease risk outcomes, as evidenced from retrospective human studies and more recent animal models 1–16 . Mechanistic examination has implicated small noncoding RNA populations in sperm, including microRNA (miRs), as carriers of paternal environmental information that consequently i...

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Literature Corpus work
311face1-5c2c-5eeb-86c7-872ae324a5e9
DOI
10.1101/321976
Open publication

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Epididymal glucocorticoid receptors promote intergenerational transmission of paternal stressDOI 10.1101/321976
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