Article
Differential susceptibility of male and female germ cells to glucocorticoid-mediated signaling
2023-07-01
Abstract excerpt
While physiologic stress has long been known to impair mammalian reproductive capacity through hormonal dysregulation, mounting evidence now suggests that stress experienced prior to or during gestation may also negatively impact the health of future offspring. Rodent models of gestational physiologic stress can induce neurologic and behavioral changes that persist for up to three generations, suggesting that stre...
Topics
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- Animal Genetics and Reproduction
- Birth, Development, and Health
- Epigenetics and DNA Methylation
- Estrogen and related hormone effects
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Reproductive Biology and Fertility
- Reproductive System and Pregnancy
- Stress Responses and Cortisol
Identifiers and source
- Literature Corpus work
- d9f4bad6-6c5a-5bbe-beb5-f0963a831969
- DOI
- 10.1101/2023.06.30.547215
