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Article

Alterations in sperm long RNA contribute to the epigenetic inheritance of the effects of postnatal trauma

26 Oct 2018

Abstract excerpt

Psychiatric diseases have a strong heritable component known to not be restricted to DNA sequence-based genetic inheritance alone but to also involve epigenetic factors in germ cells. Initial evidence suggested that sperm RNA is causally linked to the transmission of symptoms induced by traumatic experiences. Here, we show that alterations in long RNA in sperm contribute to the inheritance of specific trauma...

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PMID: 30374190
DOI: 10.1038/s41380-018-0271-6

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