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Article

Specific Pathology Features Enrich Selection of Endometrial Carcinomas for POLE Testing.

The American journal of surgical pathology - 1 Mar 2024

Keyhanian Kianoosh, Han Lucy, Howitt Brooke E, Longacre Teri

Abstract excerpt

Identification of ultramutated/ POLE -mutated endometrial carcinomas ( POLEM ECs) has important implications given its association with better prognosis. However, POLE mutation testing is not widely available. Our objective was to evaluate POLEM ECs versus POLE wild-type ( POLEWT ) ECs, within a cohort of consultation cases with features suggestive of an ultramutated phenotype. Consultation cases of EC that had...

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Share to Carcinoma, Endometrioid
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mismatch Repair Endonuclease PMS2

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Source

Identifiers

PMID: 38062789
DOI: 10.1097/PAS.0000000000002165

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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