Article
Distributed multi-objective optimization for SNP-SNP interaction detection.
Methods (San Diego, Calif.) - 1 Jan 2024
Li Fangting, Zhao Yuhai, Xu Tongze, Zhang Yuhan
Abstract excerpt
The detection of complex interactions between single nucleotide polymorphisms (SNPs) plays a vital role in genome-wide association analysis (GWAS). The multi-objective evolutionary algorithm is a promising technique for SNP-SNP interaction detection. However, as the scale of SNP data further increases, the exponentially growing search space gradually becomes the dominant factor, causing evolutionary algorithm...
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