Article
Detecting Disease-Associated SNP-SNP Interactions Using Progressive Screening Memetic Algorithm.
IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000
Guan Boxin, Zhao Yuhai, Yin Ying, Li Yuan
Abstract excerpt
Hundreds of thousands of single nucleotide polymorphisms (SNPs)are currently available for genome-wide association study (GWAS). Detecting disease-associated SNP-SNP interactions is considered an important way to capture the underlying genetic causes of complex diseases. In the combinatorially explosive search space, evolutionary algorithms are promising in solving this difficult problem because of their...
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