Article
CMDR based differential evolution identifies the epistatic interaction in genome-wide association studies.
Bioinformatics (Oxford, England) - 1 Aug 2017
Yang Cheng-Hong, Chuang Li-Yeh, Lin Yu-Da
Abstract excerpt
MOTIVATION: Detecting epistatic interactions in genome-wide association studies (GWAS) is a computational challenge. Such huge numbers of single-nucleotide polymorphism (SNP) combinations limit the some of the powerful algorithms to be applied to detect the potential epistasis in large-scale SNP datasets. APPROACH: We propose a new algorithm which combines the differential evolution (DE) algorithm with a...
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