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Article

A Novel Multitasking Ant Colony Optimization Method for Detecting Multiorder SNP Interactions.

Interdisciplinary sciences, computational life sciences - 1 Dec 2022

Tuo Shouheng, Li Chao, Liu Fan, Zhu YanLing, Chen TianRui, Feng ZengYu, Liu Haiyan, Li Aimin

Abstract excerpt

MOTIVATION: Linear or nonlinear interactions of multiple single-nucleotide polymorphisms (SNPs) play an important role in understanding the genetic basis of complex human diseases. However, combinatorial analytics in high-dimensional space makes it extremely challenging to detect multiorder SNP interactions. Most classic approaches can only perform one task (for detecting k-order SNP interactions) in each run....

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PMID: 35788965
DOI: 10.1007/s12539-022-00530-2

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