Article
Multi-objective tag SNPs selection using evolutionary algorithms.
Bioinformatics (Oxford, England) - 1 Jun 2010
Ting Chuan-Kang, Lin Wei-Ting, Huang Yao-Ting
Abstract excerpt
MOTIVATION: Integrated analysis of single nucleotide polymorphisms (SNPs) and structure variations showed that the extent of linkage disequilibrium is common across different types of genetic variants. A subset of SNPs (called tag SNPs) is sufficient for capturing alleles of bi-allelic and even multi-allelic variants. However, accuracy and power of tag SNPs are affected by several factors, including genotyping...
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