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Article

Multipopulation harmony search algorithm for the detection of high-order SNP interactions.

Bioinformatics (Oxford, England) - 15 Aug 2020

Tuo Shouheng, Liu Haiyan, Chen Hao

Abstract excerpt

MOTIVATION: Recently, multiobjective swarm intelligence optimization (SIO) algorithms have attracted considerable attention as disease model-free methods for detecting high-order single nucleotide polymorphism (SNP) interactions. However, a strict Pareto optimal set may filter out some of the SNP combinations associated with disease status. Furthermore, the lack of heuristic factors for finding SNP interactions...

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PMID: 32227192
DOI: 10.1093/bioinformatics/btaa215

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