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Article

GEP-EpiSeeker: a gene expression programming-based method for epistatic interaction detection in genome-wide association studies.

BMC genomics - 20 Dec 2021

Peng Yu Zhong, Lin Yanmei, Huang Yiran, Li Ying, Luo Guangsheng, Liao Jianping

Abstract excerpt

BACKGROUND: Identification of epistatic interactions provides a systematic way for exploring associations among different single nucleotide polymorphism (SNP) and complex diseases. Although considerable progress has been made in epistasis detection, efficiently and accurately identifying epistatic interactions remains a challenge due to the intensive growth of measuring SNP combinations. RESULTS: In this work, we...

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PMID: 34930147
DOI: 10.1186/s12864-021-08207-8
PMCID: PMC8686218

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