Article
Polymorphisms in the Runx2 and osteocalcin genes affect BMD in postmenopausal women: a systematic review and meta-analysis.
Endocrine - 1 Apr 2024
Sanyal Somali, Rajput Swati, Sadhukhan Sreyanko, Rajender Singh, Mithal Ambrish, Chattopadhyay Naibedya
Abstract excerpt
PURPOSE: Runx2 and osteocalcin have pivotal roles in bone homeostasis. Polymorphism of these two genes could alter the function of osteoblasts and consequently bone mineral density (BMD). Attempts to understand the relationship between these polymorphisms and BMD in postmenopausal women across a variety of populations have yielded inconsistent results. This meta-analysis seeks to define the relationship between...
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