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Article

Association of Gremlin-2 gene polymorphisms with osteoporosis risk in Chinese postmenopausal women.

Bioscience reports - 30 Apr 2020

Feng Yu, Zhu Lei, Gu Yong, Wang Ling-Jun, Niu Bing-Jie, Cai Feng, Chen Liang

Abstract excerpt

The Gremlin-2 (GREM2) plays crucial roles in modulating bone homeostasis through the bone morphogenetic protein-2 pathway. However, GREM2 gene variants in osteoporosis were less frequent in a Chinese population. Therefore, the present study recruited 310 patients with osteoporosis and 339 healthy postmenopausal women to assess the correlation of GREM2 gene polymorphisms with the risk of osteoporosis. Polymerase...

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Identifiers

PMID: 32297643
DOI: 10.1042/BSR20200554
PMCID: PMC7182657

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