Article
Association of SMAD2 polymorphisms with bone mineral density in postmenopausal Korean women.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Aug 2011
Kim B-J, Hwang J-Y, Han B-G, Lee J-Y, Lee J Y, Park E K, Lee S H, Chung Y-E, Kim G S, Kim S-Y, Koh J-M
Abstract excerpt
UNLABELLED: In a candidate gene association study, we found that SMAD2 promoter alleles and haplotypes were significantly associated with bone mineral density (BMD) at the lumbar spine and various proximal femur sites. Our results suggest that SMAD2 polymorphisms may be one of genetic determinants of BMD in postmenopausal women. INTRODUCTION: SMAD2, which is the specific intracellular transducer of TGF-ß, is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.