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HLA Haplotypes and Relapse After Hematopoietic Cell Transplantation

5 Dec 2023

Abstract excerpt

PURPOSE Recurrence of blood malignancy is the major cause of hematopoietic cell transplant failure. HLA class II molecules play a fundamental role in antitumor responses but the role of class II haplotypes is not known. METHODS HLA-DR, -DQ, -DM, and -DO allele variation was determined in 1,629 related haploidentical transplants to study the clinical significance of individual molecules and haplotypes. RESULTS...

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Share to Hematopoietic Stem Cell Transplantation
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PMID: 38051980
DOI: 10.1200/jco.23.01264

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