Article
HLA-DQ heterodimers in hematopoietic cell transplantation.
Blood - 19 May 2022
Petersdorf Effie W, Bengtsson Mats, Horowitz Mary, McKallor Caroline, Spellman Stephen R, Spierings Eric, Gooley Ted A, Stevenson Phil
Abstract excerpt
HLA-DQ heterodimers increase the susceptibility to autoimmune diseases, but their role in hematopoietic cell transplantation is unknown. We tested the hypothesis that outcome after HLA-matched and HLA-DQ-mismatched hematopoietic cell transplantation is influenced by HLA-DQ heterodimers. Heterodimers were defined in 5164 HLA-matched and 520 HLA-DQ-mismatched patients and their transplant donors according to...
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