Article
Patient HLA Germline Variation and Transplant Survivorship.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Aug 2018
Petersdorf Effie W, Stevenson Philip, Malkki Mari, Strong Roland K, Spellman Stephen R, Haagenson Michael D, Horowitz Mary M, Gooley Ted, Wang Tao
Abstract excerpt
Purpose HLA mismatching increases mortality after unrelated donor hematopoietic cell transplantation. The role of the patient's germline variation on survival is not known. Patients and Methods We previously identified 12 single nucleotide polymorphisms within the HLA region as markers of transplantation determinants and tested these in an independent cohort of 1,555 HLA-mismatched unrelated transplants. Linkage...
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