Article
Polygenic risk for schizophrenia predicting social trajectories in a general population sample.
Psychological medicine - 1 Jun 2024
Saarinen Aino, Hietala Jarmo, Lyytikäinen Leo-Pekka, Hamal Mishra Binisha, Sormunen Elina, Lavonius Veikka, Kähönen Mika, Raitakari Olli, Lehtimäki Terho, Keltikangas-Järvinen Liisa
Abstract excerpt
BACKGROUND: We investigated (a) whether polygenic risk for schizophrenia predicts different trajectories of social development among those who have not developed psychoses and (b) whether possible associations are PRSSCZ-specific or evident also for any polygenic risk for mental disorders, e.g. for major depression. METHODS: Participants came from the population-based Young Finns Study (n = 2377). We calculated a...
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