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Article

The apolipoprotein E polymorphism rs7412 associates with body fatness independently of plasma lipids in middle aged men.

PloS one - 1 Jan 2014

Tejedor M Teresa, Garcia-Sobreviela Maria Pilar, Ledesma Marta, Arbones-Mainar Jose M

Abstract excerpt

BACKGROUND: The apolipoprotein E (APOE) gene is polymorphic, encoding one of 3 common alleles (ε2, ε3, ε4) produced from combinations of 2 non-synonymous SNPs (rs429358 and rs7412). APOE plays an important role controlling plasma lipids but its association with adipocyte functionality and body fatness remains to be determined. METHODS: We analyzed fasting plasma lipids and genotyped the two main APOE-SNPs...

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Source

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Identifiers

PMID: 25268647
DOI: 10.1371/journal.pone.0108605
PMCID: PMC4182517

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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