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Concise Review: Cardiac Disease Modeling Using Induced Pluripotent Stem Cells

28 May 2015

Abstract excerpt

Genetic cardiac diseases are major causes of morbidity and mortality. Although animal models have been created to provide some useful insights into the pathogenesis of genetic cardiac diseases, the significant species differences and the lack of genetic information for complex genetic diseases markedly attenuate the application values of such data. Generation of induced pluripotent stem cells (iPSCs) from...

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PMID: 26033645
DOI: 10.1002/stem.2070

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