Article
Untangling the Biology of Genetic Cardiomyopathies with Pluripotent Stem Cell Disease Models.
Current cardiology reports - 1 Apr 2017
Buikema Jan W, Wu Sean M
Abstract excerpt
PURPOSE OF REVIEW: Recently, the discovery of strategies to reprogram somatic cells into induced pluripotent stem (iPS) cells has led to a major paradigm change in developmental and stem cell biology. The application of iPS cells and their cardiac progeny has opened novel directions to study cardiomyopathies at a cellular and molecular level. This review discusses approaches currently undertaken to unravel known...
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