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Article

Modelling inherited cardiac disease using human induced pluripotent stem cell-derived cardiomyocytes: progress, pitfalls, and potential.

Cardiovascular research - 1 Dec 2018

van Mil Alain, Balk Geerthe Margriet, Neef Klaus, Buikema Jan Willem, Asselbergs Folkert W, Wu Sean M, Doevendans Pieter A, Sluijter Joost P G

Abstract excerpt

In the past few years, the use of specific cell types derived from induced pluripotent stem cells (iPSCs) has developed into a powerful approach to investigate the cellular pathophysiology of numerous diseases. Despite advances in therapy, heart disease continues to be one of the leading causes of death in the developed world. A major difficulty in unravelling the underlying cellular processes of heart disease is...

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Identifiers

PMID: 30169602
DOI: 10.1093/cvr/cvy208
PMCID: PMC6887927

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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