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Article

Using Computational Simulations to Model Deleterious Variation and Genetic Load in Natural Populations.

The American naturalist - 1 Dec 2023

Kyriazis Christopher C, Robinson Jacqueline A, Lohmueller Kirk E

Abstract excerpt

AbstractDeleterious genetic variation is abundant in wild populations, and understanding the ecological and conservation implications of such variation is an area of active research. Genomic methods are increasingly used to quantify the impacts of deleterious variation in natural populations; however, these approaches remain limited by an inability to accurately predict the selective and dominance effects of...

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Identifiers

PMID: 38033186
DOI: 10.1086/726736
PMCID: PMC10897732

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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