Article
Determinants of mutation load in birds.
Genetics - 4 Apr 2026
Botero-Castro Fidel, Wolf Jochen B W
Abstract excerpt
Many mutations have detrimental effects. The mutation load in a population depends on the efficacy of purifying selection in removing deleterious genetic variation. Here, we estimated the proportion of deleterious mutations segregating in 24 population samples of 19 bird species. Exploiting the conserved avian karyotype with high variation in recombination rate and GC content, we quantified the joint effects of...
Topics
- Animals
- Mutation
- Recombination, Genetic
- Birds
- Evolution, Molecular
- Selection, Genetic
- Gene Conversion
- Population Density
- Base Composition
- Mutation Rate
- Models, Genetic