Article

When is selection effective?

2014-10-30

Abstract excerpt

Deleterious alleles can reach high frequency in small populations because of random fluctuations in allele frequency. This may lead, over time, to reduced average fitness. In that sense, selection is more ‘effective’ in larger populations. Recent studies have considered whether the different demographic histories across human populations have resulted in differences in the number, distribution, and severity of del...

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Literature Corpus work: b0ce807e-2805-5fdc-9dd2-30e5b0f11dce
DOI: 10.1101/010934

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