Article
Driver gene KRAS aggravates cancer-associated stroke outcomes.
Thrombosis research - 1 Jan 2024
Yan Haomin, Sasaki Tsutomu, Gon Yasufumi, Nishiyama Kumiko, Kanki Hideaki, Mochizuki Hideki
Abstract excerpt
The incidence of cancer-associated stroke has increased with the prolonged survival times of cancer patients. Recent genetic studies have led to progress in cancer therapeutics, but relationships between oncogenic mutations and stroke remain elusive. Here, we focused on the driver gene KRAS, which is the predominant RAS isoform mutated in multiple cancer types, in cancer associated stroke study. KRASG13D/- and...
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