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Article

Altered profiles of circulating cytokines in chronic liver diseases (NAFLD/HCC): Impact of the PNPLA3I148M risk allele.

Hepatology communications - 1 Dec 2023

Kirchmeyer Mélanie, Gaigneaux Anthoula, Servais Florence A, Arslanow Anita, Casper Markus, Krawczyk Marcin, Lammert Frank, Behrmann Iris

Abstract excerpt

BACKGROUND: Individuals carrying the risk variant p.I148M of patatin-like phospholipase domain-containing protein 3 (PNPLA3) have a higher susceptibility to fatty liver diseases and associated complications, including HCC, a cancer closely linked to chronic inflammation. Here, we assessed circulating cytokine profiles for patients with chronic liver diseases genotyped for PNPLA3. METHODS: Serum concentrations of...

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Identifiers

PMID: 38015590
DOI: 10.1097/HC9.0000000000000306
PMCID: PMC10667005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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