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Article

The PNPLA3 I148M Variant Is Associated with Immune Cell Infiltration and Advanced Fibrosis in MASLD: A Prospective Genotype-Phenotype Study

2025-05-26

Abstract excerpt

Increasing evidence reveals that immune cells significantly contribute to metabolic dysfunction-associated steatotic liver disease (MASLD) progression. The patatin-like phospholipase domain-containing protein 3 (PNPLA3) I148M variant has been linked to hepatic inflammation and fibrosis; however, its role in immune cell infiltration and activation within the liver remains unclear. Seventy patients with MASLD were p...

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Literature Corpus work
3f8baa6d-71f8-5241-883c-fadefa8afb4c
DOI
10.20944/preprints202505.1962.v1
Open publication

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The PNPLA3 I148M Variant Is Associated with Immune Cell Infiltration and Advanced Fibrosis in MASLD: A Prospective Genotype-Phenotype StudyDOI 10.20944/preprints202505.1962.v1
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