SNP array genomic analysis of matched pairs of brain and liver metastases in primary colorectal cancer.

doi:10.1007/s00432-023-05505-4

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Article

SNP array genomic analysis of matched pairs of brain and liver metastases in primary colorectal cancer.

Journal of cancer research and clinical oncology - 1 Dec 2023

Brandt Vivian-Pascal, Holland Heidrun, Wallenborn Marco, Koschny Ronald, Frydrychowicz Clara, Richter Mandy, Holland Lydia, Nestler Ulf, Sander Caroline

Abstract excerpt

PURPOSE: Brain metastasis formation is a rare and late event in colorectal cancer (CRC) patients and associated with poor survival. In contrast to other metastatic sites, the knowledge on chromosomal aberrations in brain metastases is very limited. METHODS: Therefore, we carried out single nucleotide polymorphism (SNP) array analyses on matched primary CRC and brain metastases of four patients as well as on liver...

Topics

Humans
Chromosome Aberrations
Brain
Genomics
Brain Neoplasms
Liver Neoplasms
Colorectal Neoplasms
Polymorphism, Single Nucleotide

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Identifiers

PMID: 38010391
DOI: 10.1007/s00432-023-05505-4
PMCID: PMC10725338

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