Article
Genomic profile of colon cancer metastases.
Anticancer research - 1 Jan 2000
Zeitoun Guy, Mourra Najat, Blanché-Koch Hélène, Thomas Gilles, Olschwang Sylviane
Abstract excerpt
BACKGROUND: In colon cancer, the occurrence of metastases is associated with microsatellite stability. As metastatic cells derive from a clonal expansion of primary tumor cells, specific genomic alterations are expected in addition to the common genomic profile. PATIENTS AND METHODS: Genome-wide allelotyping was performed on 75 liver metastases samples from sporadic colon cancer. RESULTS: No microsatellite...
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