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Article

Genomic profiling and identification of high-risk uveal melanoma by array CGH analysis of primary tumors and liver metastases.

Investigative ophthalmology & visual science - 1 Jun 2009

Trolet Julien, Hupé Philippe, Huon Isabelle, Lebigot Ingrid, Decraene Charles, Delattre Olivier, Sastre-Garau Xavier, Saule Simon, Thiéry Jean-Paul, Plancher Corine, Asselain Bernard, Desjardins Laurence, Mariani Pascale, Piperno-Neumann Sophie, Barillot Emmanuel, Couturier Jérôme

Abstract excerpt

PURPOSE: Incurable metastases develop in approximately 50% of patients with uveal melanoma (UM). The purpose of this study was to analyze genomic profiles in a large series of ocular tumors and liver metastases and design a genome-based classifier for metastatic risk assessment. METHODS: A series of 86 UM tumors and 66 liver metastases were analyzed by using a BAC CGH (comparative genomic hybridization)...

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Share to Chromosomes, Human, Pair 3
Share to Comparative Genomic Hybridization

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Liver Neoplasms

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Share to Monosomy

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Source

Identifiers

PMID: 19151381
DOI: 10.1167/iovs.08-2296

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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