Article
High resolution genome-wide SNP array analyses on matched colorectal-based lung and brain metastases.
Journal of cancer research and clinical oncology - 30 Jan 2026
Brandt Vivian-Pascal, Sander Carolin, Holland Lydia, Koschny Ronald, Müller Wolf C, Bläker Hendrik, Nestler Ulf, Güresir Erdem, Holland Heidrun
Abstract excerpt
PURPOSE: Colorectal-based brain metastasis formation is a rare and late event in colorectal cancer (CRC) patients and is associated with poor survival. Compared with other metastatic sites, the knowledge about copy number variation (CNV) in brain metastases is still very limited. To get more information about CNVs, we applied SNP array to analyze chromosomal regions with a higher density of SNP markers. METHODS:...
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