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Article

Specific genomic aberrations in primary colorectal cancer are associated with liver metastases.

BMC cancer - 2 Dec 2010

Bruin Sjoerd C, Klijn Christiaan, Liefers Gerrit-Jan, Braaf Linde M, Joosse Simon A, van Beers Eric H, Verwaal Victor J, Morreau Hans, Wessels Lodewyk F, van Velthuysen Marie-Louise F, Tollenaar Rob A E M, Van't Veer Laura J

Abstract excerpt

BACKGROUND: Accurate staging of colorectal cancer (CRC) with clinicopathological parameters is important for predicting prognosis and guiding treatment but provides no information about organ site of metastases. Patterns of genomic aberrations in primary colorectal tumors may reveal a chromosomal signature for organ specific metastases. METHODS: Array Comparative Genomic Hybridization (aCGH) was employed to asses...

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PMID: 21126340
DOI: 10.1186/1471-2407-10-662
PMCID: PMC3027605

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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