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Article

Genomic profiling of tissue and blood predicts survival outcomes in patients with resected pleural mesothelioma.

European journal of cancer (Oxford, England : 1990) - 1 Jan 2024

de Miguel-Perez Diego, Pickering Edward M, Malapelle Umberto, Grier William, Pepe Francesco, Pisapia Pasquale, Russo Gianluca, Pinto Joseph A, Russo Alessandro, Troncone Giancarlo, Culligan Melissa J, Scilla Katherine A, Mehra Ranee, Mohindra Pranshu, Arrieta Oscar, Cardona Andres F, Del Re Marzia, Sachdeva Ashutosh, Hirsch Fred R, Wolf Andrea, Friedberg Joseph S, Rolfo Christian

Abstract excerpt

PURPOSE: Pleural mesothelioma (PM) is an aggressive tumor still considered incurable, in part due to the lack of predictive biomarkers. Little is known about the clinical implications of molecular alterations in resectable PM tissues and blood. Here, we characterized genetic alterations to identify prognostic and predictive biomarkers in patients with resected PM. EXPERIMENTAL DESIGN: Targeted next-generation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 38008032
DOI: 10.1016/j.ejca.2023.113457

Genes

MAF
EPHB1
KMT2C
LIFR
PBRM1
PKHD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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