Article
Genomic characterization and detection of potential therapeutic targets for peritoneal mesothelioma in current practice.
Clinical and experimental medicine - 20 Apr 2024
van Kooten Job P, Dietz Michelle V, Dubbink Hendrikus Jan, Verhoef Cornelis, Aerts Joachim G J V, Madsen Eva V E, von der Thüsen Jan H
Abstract excerpt
Peritoneal mesothelioma (PeM) is an aggressive tumor with limited treatment options. The current study aimed to evaluate the value of next generation sequencing (NGS) of PeM samples in current practice. Foundation Medicine F1CDx NGS was performed on 20 tumor samples. This platform assesses 360 commonly somatically mutated genes in solid tumors and provides a genomic signature. Based on the detected mutations,...
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